What is the most common composition of neutral spheres used as core for active pellets?

The most common composition is sucrose and maize starch, providing an inert, digestible and biodegradable starter core for drug layering and pellet coating.

Does the hygroscopic starch interfere with water-sensitive active substances?

No. The starch is bound within the sphere matrix and does not release moisture to water-sensitive APIs under standard storage and processing conditions.

Are customized particle size distributions (PSD) available?

Yes. Besides the standard size range from 100 µm to 2 mm, tailor-made and reproducible particle size distributions can be produced on request (higher minimum order quantities may apply).

Are the sugar spheres suitable for regulatory drug applications worldwide?

Yes. The spheres comply with Ph.Eur. and USP/NF, are produced under ISO 9001 and IPEC GMP standards, and an FDA Drug Master File (DMF) is available to support global registrations.

Pure Carriers for Homeopathic Excellence

pharm-a-spheres™ Globuli Sacchari

HAB-Conforming Globuli Sacchari Manufactured to Pharmaceutical Standards

pharm-a-spheres™ offers a comprehensive range of high-quality pharmaceutical excipients, manufactured to the most stringent international standards.

Pure & Available in All HAB Sizes

Our production process ensures the highest purity and consistency, meeting the quality expectations of homeopathic manufacturers worldwide. Whether you require standard formulations or custom specifications, our expert team is ready to support your production needs.

Pharm-a-spheres™ globuli sacchari are premium inert carriers for homeopathic preparations, manufactured from pure sucrose in full conformity with the German Homeopathic Pharmacopoeia (HAB). Free from additional excipients and preservatives, they are available in every standard size – from HAB No. 1 to No. 10. Furthermore specialties are available, like in sugar-free xylitol variants and Sucrose/Lactose variants.

Historical Excellence Meets Modern Quality

Following the tradition established by Samuel Hahnemann (1755-1843), the founder of homeopathy, we manufacture globuli using both traditional recipes and modern pharmacopoeia requirements. Our product range encompasses all standard types and sizes, with the flexibility to fulfill special requests.

Sugar-free Options

Xylitol or xylitol/calcium carbonate globuli for special applications.

French Pharmacopoeia Standard

Sucrose and lactose blend globuli.

Hahnemann Original Recipe

Traditional formulation using sucrose and starch.

HAB-Conforming Globuli

Pure sucrose globuli meeting German Homeopathic Pharmacopoeia standards (sizes 1-10).

Homeopathic Globules from Germany – Quality Since 1952

Hanns G. Werner GmbH + Co. KG is a medium-sized, family-owned company, specialized on sugar spheres and globuli sacchari. For several decades our company is growing at the site in Tornesch, near the city of Hamburg. On an area of more than 11,000 square meters we are manufacturing 6,000 t of spheres per year.

About us